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- Q Q：355185756
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- 地址：安徽省合肥市高新區(qū)黃山路602號(hào)合肥國(guó)家大學(xué)科技園A401室
Anti -cIAP2 Rabbit pAb
價(jià)格：
在線(xiàn)咨詢(xún)
貨號(hào)：
KT012191
產(chǎn)品規(guī)格：
100ul
Applications：
WB|IHC/IF
Species：
M/R,M/R
購(gòu)買(mǎi)數(shù)量：
產(chǎn)品詳情
操作說(shuō)明
注意事項(xiàng)
Product Information
|
Description |
cIAP2 rabbit polyclonal antibody |
|
Protein full name |
Baculoviral IAP repeat-containing protein 3 |
|
Synonyms |
Cellular inhibitor of apoptosis 2, C-IAP2, Birc3, Inhibitor of apoptosis protein 1, mIAP1, RING-type E3 ubiquitin transferase BIRC3 |
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse cIAP2 |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Subcellular location |
Nucleus, Cytoplasm |
|
Predicted MW. |
67 kDa |
|
Observed MW. |
67 kDa |
|
Uniprot ID |
O08863, Q5XIW4 |
Applications
|
Applications |
Species |
Dilution |
Positive Sample |
|
WB |
Mouse, Rat |
1: 500-1: 1000 |
thymus, testis, lymph node |
|
IHC/IF |
Mouse, Rat |
1: 750-1: 3000 |
lung, lymph node, spleen, testis |
Background
Multi-functional protein which regulates not only caspases and apoptosis, but also modulates inflammatory signaling and immunity, mitogenic kinase signaling and cell proliferation, as well as cell invasion and metastasis. Acts as an E3 ubiquitin- protein ligase regulating NF-kappa-B signaling and regulates both canonical and non-canonical NF-kappa-B signaling by acting in opposite directions: acts as a positive regulator of the canonical pathway and suppresses constitutive activation of non-canonical NF-kappa-B signaling. Protects cells from spontaneous formation of the ripoptosome, a large multi-protein complex that has the capability to kill cancer cells in a caspase dependent and caspase independent manner.
Images
|
Western blot analysis of BIRC3 (GB111051) at dilution of 1: 500 |
|
Immunohistochemistry of paraffin embedded mouse lung using BIRC3 (GB111051) at dilution of 1: 1800 (400x lens) |
|
Immunohistochemistry of paraffin embedded mouse lymph node using BIRC3 (GB111051) at dilution of 1: 1800 (400x lens) |
|
Immunohistochemistry of paraffin embedded mouse spleen using BIRC3 (GB111051) at dilution of 1: 1800 (400x lens) |
|
Immunohistochemistry of paraffin embedded mouse testis using BIRC3 (GB111051) at dilution of 1: 1800 (400x lens) |
|
Immunofluorescence of paraffin embedded mouse lung using BIRC3 (GB111051) at dilution of 1: 1000 (400x lens) |
|
Immunofluorescence of paraffin embedded mouse lymph node using BIRC3 (GB111051) at dilution of 1: 1000 (400x lens) |
|
Immunofluorescence of paraffin embedded mouse spleen using BIRC3 (GB111051) at dilution of 1: 1000 (400x lens) |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥萬(wàn)物生物科技有限公司
客服熱線(xiàn)：400-1016-218
QQ：355185756
地址：安徽省合肥市高新區(qū)黃山路602號(hào)合肥國(guó)家大學(xué)科技園A401室