Anti -DKK2 Rabbit pAb

價格：在線咨詢

貨號：

KT012233

產(chǎn)品規(guī)格：

100 μL

Applications：

Species：

品牌：

萬物

購買數(shù)量：

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產(chǎn)品詳情操作說明注意事項

Product Information

Description	DKK2 rabbit polyclonal antibody
Protein full name	Dickkopf-related protein 2
Synonyms	Dickkopf-2, Dickkopf related protein 2, DKK-2, DKK2, hDkk 2, mDkk-2
Immunogen	KLH conjugated Synthetic peptide corresponding to Mouse DKK2
Isotype	IgG
Purity	Affinity purification
Predicted MW.	28 kDa
Observed MW.	28 kDa
Uniprot ID	Q9QYZ8

Applications

Applications	Species	Dilution	Positive Sample
WB	Mouse	1: 1000-1: 2000	kidney, heart, lung

Background

Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.

Images

Western blot analysis of DKK2 (GB113829) at dilution of 1: 2000

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer	PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.

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